| CRNX |
Crinetics Pharmaceuticals, Inc. |
3.15B |
3.68% |
|
|
|
|
|
33.62 |
0.69% |
70.01% |
18.21% |
|---|
| ALKS |
Alkermes plc |
4.96B |
3.65% |
|
|
|
|
|
30.11 |
4.66% |
55.46% |
121.60% |
|---|
| AXSM |
Axsome Therapeutics, Inc. |
5.42B |
3.22% |
|
|
|
|
|
111.21 |
-0.96% |
49.12% |
29.52% |
|---|
| VRNA |
Verona Pharma plc |
6.19B |
3.01% |
|
|
|
|
|
72.80 |
1.01% |
57.13% |
29.37% |
|---|
| PTCT |
PTC Therapeutics, Inc. |
3.89B |
2.77% |
|
|
|
|
|
49.27 |
-1.14% |
48.14% |
95.97% |
|---|
| RNA |
Avidity Biosciences, Inc. |
3.85B |
2.73% |
|
|
|
|
|
31.99 |
-2.02% |
67.15% |
60.34% |
|---|
| RYTM |
Rhythm Pharmaceuticals, Inc. |
4.09B |
2.71% |
|
|
|
|
|
64.38 |
-1.24% |
54.39% |
39.04% |
|---|
| MLTX |
MoonLake Immunotherapeutics |
2.57B |
2.62% |
|
|
|
|
|
40.46 |
-3.85% |
81.70% |
30.35% |
|---|
| XENE |
Xenon Pharmaceuticals Inc. |
2.94B |
2.30% |
|
|
|
|
|
38.46 |
0.68% |
55.26% |
44.91% |
|---|
| DNLI |
Denali Therapeutics Inc. |
2.33B |
2.28% |
|
|
|
|
|
16.06 |
-3.57% |
64.25% |
57.34% |
|---|
| ZLAB |
Zai Lab Limited |
342.45M |
2.27% |
|
|
|
|
|
31.24 |
-1.44% |
123.26% |
27.88% |
|---|
| MRUS |
Merus N.V. |
3.10B |
2.25% |
|
|
|
|
|
44.82 |
-1.52% |
47.93% |
43.51% |
|---|
| FOLD |
Amicus Therapeutics, Inc. |
2.10B |
2.20% |
|
|
|
|
|
6.82 |
-11.26% |
51.71% |
52.97% |
|---|
| ACAD |
ACADIA Pharmaceuticals Inc. |
2.42B |
2.18% |
|
|
|
|
|
14.53 |
-0.48% |
52.38% |
77.59% |
|---|
| VCEL |
Vericel Corporation |
1.91B |
2.14% |
|
|
|
|
|
38.13 |
0.29% |
58.27% |
85.41% |
|---|
| VERA |
Vera Therapeutics, Inc. |
1.46B |
2.09% |
|
|
|
|
|
22.97 |
-1.71% |
65.71% |
88.52% |
|---|
| EWTX |
Edgewise Therapeutics, Inc. |
1.75B |
2.01% |
|
|
|
|
|
16.60 |
1.22% |
89.13% |
12.77% |
|---|
| NAMS |
NewAmsterdam Pharma Company N.V. |
2.18B |
1.85% |
|
|
|
|
|
19.87 |
3.87% |
113.43% |
32.08% |
|---|
| PTGX |
Protagonist Therapeutics, Inc. |
2.76B |
1.80% |
|
|
|
|
|
44.97 |
-1.87% |
68.70% |
22.08% |
|---|
| IDYA |
IDEAYA Biosciences, Inc. |
1.75B |
1.69% |
|
|
|
|
|
19.99 |
-0.70% |
142.62% |
46.95% |
|---|
| TARS |
Tarsus Pharmaceuticals, Inc. |
2.08B |
1.64% |
|
|
|
|
|
49.98 |
-3.72% |
72.63% |
25.46% |
|---|
| APGE |
Apogee Therapeutics, Inc. |
2.34B |
1.58% |
|
|
|
|
|
39.40 |
0.38% |
66.75% |
66.98% |
|---|
| MIRM |
Mirum Pharmaceuticals, Inc. |
2.14B |
1.55% |
|
|
|
|
|
43.33 |
-0.28% |
49.91% |
40.08% |
|---|
| AKRO |
Akero Therapeutics, Inc. |
3.62B |
1.53% |
|
|
|
|
|
45.49 |
-0.26% |
73.43% |
13.69% |
|---|
| CGON |
CG Oncology, Inc. Common stock |
2.07B |
1.51% |
|
|
|
|
|
27.13 |
0.71% |
102.73% |
71.29% |
|---|
| AGIO |
Agios Pharmaceuticals, Inc. |
1.77B |
1.48% |
|
|
|
|
|
30.52 |
2.80% |
67.83% |
50.52% |
|---|
| IRON |
Disc Medicine, Inc. |
1.72B |
1.44% |
|
|
|
|
|
49.67 |
0.51% |
76.09% |
50.44% |
|---|
| GLPG |
Galapagos NV |
1.77B |
1.41% |
|
|
|
|
|
26.90 |
-0.07% |
72.56% |
31.73% |
|---|
| MNKD |
MannKind Corporation |
1.50B |
1.41% |
|
|
|
|
|
4.94 |
-2.08% |
234.87% |
55.39% |
|---|
| NMRA |
Neumora Therapeutics, Inc. Common Stock |
118.69M |
1.40% |
|
|
|
|
|
0.7338 |
-5.90% |
105.51% |
50.00% |
|---|
| CLDX |
Celldex Therapeutics, Inc. |
1.36B |
1.31% |
|
|
|
|
|
20.43 |
-1.92% |
48.11% |
43.73% |
|---|
| XNCR |
Xencor, Inc. |
768.08M |
1.30% |
|
|
|
|
|
10.80 |
-2.04% |
81.40% |
44.47% |
|---|
| BCRX |
BioCryst Pharmaceuticals, Inc. |
1.86B |
1.22% |
|
|
|
|
|
8.88 |
0.28% |
50.70% |
55.74% |
|---|
| VRDN |
Viridian Therapeutics, Inc. |
1.11B |
1.21% |
|
|
|
|
|
13.63 |
0.59% |
48.83% |
33.83% |
|---|
| GPCR |
Structure Therapeutics Inc. |
507.37M |
1.19% |
|
|
|
|
|
26.57 |
-1.59% |
82.10% |
16.95% |
|---|
| IMCR |
Immunocore Holdings plc |
1.50B |
1.14% |
|
|
|
|
|
30.06 |
-0.13% |
80.23% |
38.19% |
|---|
| PRAX |
Praxis Precision Medicines, Inc. |
771.95M |
1.11% |
|
|
|
|
|
38.29 |
1.71% |
167.62% |
30.04% |
|---|
| RCUS |
Arcus Biosciences, Inc. |
897.38M |
1.07% |
|
|
|
|
|
8.48 |
-3.14% |
286.49% |
39.78% |
|---|
| AUPH |
Aurinia Pharmaceuticals Inc. |
1.12B |
1.03% |
|
|
|
|
|
8.22 |
-0.30% |
72.96% |
36.74% |
|---|
| NVAX |
Novavax, Inc. |
1.04B |
1.00% |
|
|
|
|
|
6.45 |
-3.37% |
70.09% |
49.53% |
|---|
| DAWN |
Day One Biopharmaceuticals, Inc. |
770.29M |
0.99% |
|
|
|
|
|
7.60 |
-2.31% |
62.90% |
63.95% |
|---|
| NTLA |
Intellia Therapeutics, Inc. |
891.80M |
0.91% |
|
|
|
|
|
8.62 |
-2.87% |
84.48% |
66.92% |
|---|
| PHVS |
Pharvaris N.V. |
947.91M |
0.81% |
|
|
|
|
|
17.40 |
-5.87% |
N/A |
N/A |
|---|
| VIR |
Vir Biotechnology, Inc. |
838.74M |
0.79% |
|
|
|
|
|
6.08 |
-0.74% |
70.90% |
53.75% |
|---|
| LQDA |
Liquidia Corporation |
1.20B |
0.76% |
|
|
|
|
|
14.09 |
0.82% |
66.08% |
36.28% |
|---|
| AVXL |
Anavex Life Sciences Corp. |
788.55M |
0.73% |
|
|
|
|
|
9.27 |
-2.42% |
98.87% |
20.65% |
|---|
| REPL |
Replimune Group, Inc. |
751.66M |
0.73% |
|
|
|
|
|
9.76 |
-0.20% |
122.01% |
14.82% |
|---|
| UPB |
Upstream Bio Inc. |
|
0.72% |
|
|
|
|
|
|
|
|
|
|---|
| AVBP |
ArriVent BioPharma, Inc. Common Stock |
713.66M |
0.71% |
|
|
|
|
|
20.98 |
-1.32% |
N/A |
6.74% |
|---|
| NUVB |
Nuvation Bio Inc. |
753.71M |
0.69% |
|
|
|
|
|
2.2255 |
-1.09% |
256.22% |
29.99% |
|---|
| PRTA |
Prothena Corporation plc |
472.87M |
0.63% |
|
|
|
|
|
8.79 |
-4.51% |
80.41% |
55.36% |
|---|
| PLRX |
Pliant Therapeutics, Inc. |
96.38M |
0.61% |
|
|
|
|
|
1.5700 |
-1.26% |
117.25% |
39.13% |
|---|
| ERAS |
Erasca, Inc. |
409.32M |
0.57% |
|
|
|
|
|
1.4450 |
-1.03% |
364.07% |
47.06% |
|---|
| IRWD |
Ironwood Pharmaceuticals, Inc. |
148.56M |
0.55% |
|
|
|
|
|
0.9181 |
-1.52% |
191.36% |
51.06% |
|---|
| RAPP |
Rapport Therapeutics Inc. |
|
0.53% |
|
|
|
|
|
|
|
|
|
|---|
| IMNM |
Immunome, Inc. |
768.31M |
0.50% |
|
|
|
|
|
8.83 |
0.46% |
145.43% |
80.99% |
|---|
| DNTH |
Dianthus Therapeutics, Inc. |
688.46M |
0.50% |
|
|
|
|
|
21.43 |
-1.92% |
101.76% |
-3.33% |
|---|
| CRGX |
CARGO Therapeutics, Inc. Common Stock |
206.31M |
0.50% |
|
|
|
|
|
4.48 |
-1.97% |
116.77% |
61.50% |
|---|
| KROS |
Keros Therapeutics, Inc. |
584.80M |
0.50% |
|
|
|
|
|
14.40 |
-0.28% |
87.60% |
39.15% |
|---|
| CAPR |
Capricor Therapeutics, Inc. |
590.60M |
0.49% |
|
|
|
|
|
12.93 |
1.81% |
128.94% |
36.28% |
|---|
| MLYS |
Mineralys Therapeutics, Inc. |
963.41M |
0.49% |
|
|
|
|
|
14.85 |
4.50% |
399.28% |
14.59% |
|---|
| MBX |
MBX Biosciences Inc. |
|
0.47% |
|
|
|
|
|
|
|
|
|
|---|
| AUTL |
Autolus Therapeutics plc |
356.61M |
0.46% |
|
|
|
|
|
1.3400 |
-4.96% |
378.96% |
28.63% |
|---|
| STOK |
Stoke Therapeutics, Inc. |
532.67M |
0.45% |
|
|
|
|
|
9.85 |
0.92% |
405.70% |
50.16% |
|---|
| FLGT |
Fulgent Genetics, Inc. |
527.80M |
0.44% |
|
|
|
|
|
17.10 |
-1.44% |
88.61% |
39.52% |
|---|
| ANNX |
Annexon, Inc. |
199.13M |
0.43% |
|
|
|
|
|
1.8150 |
-2.42% |
222.49% |
30.55% |
|---|
| SVRA |
Savara Inc. |
555.88M |
0.41% |
|
|
|
|
|
3.22 |
0.63% |
110.17% |
17.19% |
|---|
| TRML |
Tourmaline Bio, Inc. |
435.22M |
0.40% |
|
|
|
|
|
16.95 |
-1.54% |
217.10% |
56.76% |
|---|
| ATXS |
Astria Therapeutics, Inc. |
290.07M |
0.39% |
|
|
|
|
|
5.14 |
-0.39% |
104.44% |
27.99% |
|---|
| CELC |
Celcuity Inc. |
411.88M |
0.38% |
|
|
|
|
|
10.89 |
-2.29% |
192.76% |
59.68% |
|---|
| RNAC |
Cartesian Therapeutics, Inc. |
316.07M |
0.37% |
|
|
|
|
|
12.20 |
1.67% |
588.62% |
87.69% |
|---|
| TBPH |
Theravance Biopharma, Inc. |
497.26M |
0.37% |
|
|
|
|
|
9.95 |
1.79% |
309.67% |
45.58% |
|---|
| ARCT |
Arcturus Therapeutics Holdings Inc. |
340.35M |
0.35% |
|
|
|
|
|
12.55 |
-2.03% |
84.60% |
48.93% |
|---|
| URGN |
UroGen Pharma Ltd. |
516.95M |
0.35% |
|
|
|
|
|
11.22 |
-3.65% |
386.64% |
64.85% |
|---|
| AURA |
Aura Biosciences, Inc. |
298.60M |
0.32% |
|
|
|
|
|
5.94 |
1.89% |
196.57% |
34.68% |
|---|
| ANAB |
AnaptysBio, Inc. |
662.71M |
0.32% |
|
|
|
|
|
21.61 |
-2.75% |
164.29% |
29.87% |
|---|
| ZBIO |
ProShares UltraPro Short Nasdaq Biotechn... |
|
0.29% |
|
|
|
|
|
11.28 |
-2.63% |
N/A |
N/A |
|---|
| YMAB |
Y-mAbs Therapeutics, Inc. |
184.26M |
0.27% |
|
|
|
|
|
4.08 |
-4.12% |
299.13% |
61.45% |
|---|
| OLMA |
Olema Pharmaceuticals, Inc. |
350.89M |
0.25% |
|
|
|
|
|
5.14 |
-0.48% |
252.67% |
47.23% |
|---|
| SLRN |
Acelyrin, Inc. |
263.87M |
0.24% |
|
|
|
|
|
2.6150 |
5.87% |
333.04% |
41.28% |
|---|
| ALDX |
Aldeyra Therapeutics, Inc. |
162.71M |
0.23% |
|
|
|
|
|
2.7250 |
2.83% |
257.76% |
96.21% |
|---|
| RIGL |
Rigel Pharmaceuticals, Inc. |
340.10M |
0.23% |
|
|
|
|
|
19.04 |
-2.68% |
88.68% |
6.25% |
|---|
| RZLT |
Rezolute, Inc. |
316.75M |
0.22% |
|
|
|
|
|
3.90 |
3.59% |
300.54% |
48.32% |
|---|
| VNDA |
Vanda Pharmaceuticals Inc. |
262.85M |
0.22% |
|
|
|
|
|
4.46 |
-1.11% |
86.92% |
32.39% |
|---|
| ITOS |
iTeos Therapeutics, Inc. |
283.03M |
0.21% |
|
|
|
|
|
7.40 |
2.00% |
641.47% |
66.63% |
|---|
| AMLX |
Amylyx Pharmaceuticals, Inc. |
487.74M |
0.21% |
|
|
|
|
|
5.48 |
7.14% |
307.72% |
48.94% |
|---|
| CMPS |
COMPASS Pathways plc |
279.07M |
0.20% |
|
|
|
|
|
4.07 |
2.28% |
216.18% |
82.80% |
|---|
| LRMR |
Larimar Therapeutics, Inc. |
174.48M |
0.20% |
|
|
|
|
|
2.7250 |
2.83% |
265.15% |
52.65% |
|---|
| ELDN |
Eledon Pharmaceuticals, Inc. |
197.61M |
0.19% |
|
|
|
|
|
3.30 |
4.43% |
161.70% |
58.49% |
|---|
| FDMT |
4D Molecular Therapeutics, Inc. |
153.03M |
0.19% |
|
|
|
|
|
3.31 |
-1.93% |
245.06% |
81.97% |
|---|
|
Cash and Equivalents |
|
0.19% |
|
|
|
|
|
|
|
|
|
|---|
| PROK |
ProKidney Corp. |
254.47M |
0.18% |
|
|
|
|
|
0.8694 |
-1.83% |
595.08% |
60.01% |
|---|
| ZNTL |
Zentalis Pharmaceuticals, Inc. |
103.77M |
0.16% |
|
|
|
|
|
1.4450 |
1.76% |
370.78% |
59.67% |
|---|
| MGNX |
MacroGenics, Inc. |
105.68M |
0.16% |
|
|
|
|
|
1.6750 |
-3.46% |
120.94% |
50.24% |
|---|
| ACRS |
Aclaris Therapeutics, Inc. |
148.89M |
0.14% |
|
|
|
|
|
1.3750 |
-0.36% |
94.58% |
55.16% |
|---|
| ALEC |
Alector, Inc. |
114.99M |
0.13% |
|
|
|
|
|
1.1500 |
-4.17% |
666.34% |
100.00% |
|---|
| KYTX |
Kyverna Therapeutics, Inc. |
97.67M |
0.12% |
|
|
|
|
|
2.2600 |
-2.16% |
634.61% |
46.90% |
|---|
| STRO |
Sutro Biopharma, Inc. |
83.49M |
0.12% |
|
|
|
|
|
0.9897 |
-5.74% |
579.44% |
61.26% |
|---|
| ENTA |
Enanta Pharmaceuticals, Inc. |
130.13M |
0.10% |
|
|
|
|
|
6.10 |
0.16% |
220.08% |
81.98% |
|---|
| 1835589D |
Chinook Therapeutics Inc. |
|
N/A |
|
|
|
|
|
|
|
|
|
|---|